Flotillin family protein
WebJul 11, 2005 · Text Box 1. Flotillin-2 discovery: Flotillin-2 was actually the first member of the flotillin family to be cloned. However, it was unwittingly discovered in a hybridoma … Webanalysis of the cDNA for this protein has provided new avenues by which to explore the structure and function of caveolae organelles. Interestingly, flotillin is a close homologue …
Flotillin family protein
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WebMar 26, 2024 · Flotillin-1 and flotillin-2 are ubiquitously expressed, membrane-associated proteins involved in multifarious cellular events from cell signaling, endocytosis, and … WebMar 1, 2013 · We will not only review the well-known members of the family, such as kinase suppressor of Ras (KSR), but also put a special focus on the function of the recently identified or less studied scaffolders, such as fibroblast growth factor receptor substrate 2, flotillin-1 and mitogen-activated protein kinase organizer 1.
WebFlotillin-1 is a close homolog of the Epidermal Surface Antigen (ESA/Flotillin-2), which also colocalizes in the caveolae. Thus, Flotillin-1 and its relative ESA/Flotillin-2 are now … WebJul 14, 2024 · The bacterial plasma membrane is an important cellular compartment. In recent years it has become obvious that protein complexes and lipids are not uniformly distributed within membranes. Current hypotheses suggest that flotillin proteins are required for the formation of complexes of membrane proteins including cell-wall …
WebNov 27, 2009 · Calcium spiking appears to control activity of a calcium/calmodulin-dependent protein kinase and two downstream GRAS-family transcription factors, … WebMar 1, 2008 · The flotillin-2 protein induction was observed as early as 12 hours after TAp73β or TAp63γ overexpression. Even when Saos-2 cells were infected with Ad-p53 …
WebApr 10, 2024 · Herpesvirus envelope glycoprotein B (gB) is one of the best-documented extracellular vesicle (EVs)-incorporated viral proteins. Regarding the sequence and structure conservation between gB homologs, we asked whether bovine herpesvirus-1 (BoHV-1) and pseudorabies virus (PRV)-encoded gB share the property of herpes simplex-1 (HSV-1) …
WebOct 1, 2005 · The flotillin family is composed of two highly homologous proteins, flotillin 1 and flotillin 2, characterized by the presence of a prohibitin homology (PHB) domain, which is responsible for ... easydncWebImmunoprecipitation of flotillin-1 protein from BT-20 cell extracts. Lane 1 is 10% input, lane 2 is Rabbit (DA1E) mAb IgG XP ® Isotype Control #3900, and lane 3 is Flotillin-1 (D2V7J) XP ® Rabbit mAb. Western blot analysis was performed using Flotillin-1 (D2V7J) XP ® Rabbit mAb. Show Less Show More easy diy wood christmas giftsWebMay 24, 2016 · Flotillin-1 (Flot1, reggie-2) is a lipid raft-associated scaffolding protein that belongs to a family of proteins characterized by an evolutionarily conserved SPFH domain (Browman et al., 2007; Langhorst et al., 2008).Although flotillin-1 is ubiquitously expressed, it is known to be highly expressed in brain tissue, and has been shown to serve distinct … easydl零门槛ai开发平台WebMar 21, 2024 · Flotillin-1 protein is upregulated in human endometrial cancer and localization shifts from epithelial to stromal with increasing tumor grade; ... ATP-binding cassette, sub-family A (ABC1), member 1 forms a complex with syntaxin 13 and flotillin-1, residing at the plasma membrane and in phagosomes; easy dmx controllerWebThe flotillin family is composed of two highly homologous proteins, flotillin-1 and flotillin-2 that share ~50% amino acid sequence similarity. ... Human Flotillin-1 recombinant protein corresponding to amino acids 1-270 expressed in E. coli. Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Preparation The ... easydna south africa sandtonWebFlotillin 2 is a direct transcriptional target of the p53 family member genes in human cancer cells. The interaction of flotillin-2 with amyloid precursor protein (APP) promotes the clustering of APP at the cell surface. Coassembly of flotillin1 and flotillin2 into microdomains induces membrane curvature, the formation of plasma-membrane ... easy dncWebOct 4, 2005 · May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. Sequence similarities. Belongs to the band 7/mec-2 family. Flotillin subfamily. Cellular localization. Cell membrane. Membrane > caveola. Melanosome. Endosome. Membrane-associated … easydnnnews