WebOct 31, 2016 · Abstract. Accumulating preclinical and clinical evidence indicates that the success of several anticancer agents—including some conventional chemotherapeutics, targeted anticancer agents as well as specific forms of radiotherapy—depends (at least in part) on their ability to stimulate anticancer immune responses. Such immunostimulatory … WebApr 1, 2015 · This said, regulated instances of cell death that causally depend on the autophagic machinery have been described (Denton et al, 2009; Denton et al, 2012b; …
Molecular definitions of autophagy and related processes.
WebGalluzzi L, Vitale I, Warren S, Adjemian Catani S, Agostinis P, Martinez AB, et al. Consensus guidelines for the definition, detection and interpretation of immunogenic cell death. JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2024;8(1). WebAug 11, 2016 · Moreover, CR constitutes an efficient inducer of autophagy in human tissues, and this has multiple anti-aging effects as it promotes efficient quality control on organelles, supports optimal stem cell activity, improves immunological functions, and inhibits malignant transformation (Galluzzi et al., 2015). the punisher marvel database
Autophagy in malignant transformation and cancer progression
WebDec 8, 2024 · EMBO J 2015; 34:856–880. Article CAS PubMed PubMed Central Google Scholar Rosenfeldt MT, O'Prey J, Morton JP, et al. p53 status ... Galluzzi L, Senovilla L, Vitale I, et al. Molecular mechanisms ... WebNov 10, 2024 · Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, et al. Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ. 2009; 16:1093–1107. doi: 10.1038/cdd.2009.44. [PMC free article] [Google Scholar] WebThe tremendous clinical success of checkpoint blockers illustrates the potential of reestablishing latent immunosurveillance for cancer therapy. Although largely neglected in the clinical practice, accumulating evidence indicates that the efficacy of conventional and targeted anticancer agents does not only involve direct cytostatic/cytotoxic effects, but … the punisher ma gnucci