WebApr 11, 2024 · Objective SLE is an autoimmune disease characterised by persistent inflammation and autoantibody production. Genetic predisposition and environmental factors such as a high-fat diet (HFD) may contribute to lupus development. However, the immune cell profile and gender difference in response to HFD in lupus have not been … WebAug 2, 2024 · Male GDF15 knockout mice were more prone to high fat diet-induced obesity than wildtype mice. At 9 weeks of age, the wildtype and knockout mice had similar body …
Diet-Induced Obese C57BL/6J The Jackson Laboratory
WebAug 11, 2024 · Adipose tissue is a major regulator of metabolic health ().Obesity is a significant health problem (1, 2), which broadly refers to excess adipose tissue.It is accompanied by increases in type 2 diabetes and cardiometabolic disease, the conditions linked to insulin resistance and glucose intolerance (1, 3).One of the main pathological … WebMay 17, 2013 · PXR ablation inhibited HFD-induced obesity. To evaluate the function of PXR in energy metabolism, age-matched wild-type (WT) and PXR −/− mice were fed with normal chow diet or HFD for 12 weeks. Under the chow diet, PXR −/− and WT mice were not different in their body weights (data not shown) and total fat or lean content … immunoadsorption名词解释
C57BL/6J substrain differences in response to high-fat …
WebMale C57BL/6J DIO mice were fed D12492 60 kcal% fat and Control mice were fed D12450B 10 kcal% fat diet between the ages of 6 and 30 weeks. Values represent mean and one standard deviation of at least 90 DIO and 30 Control mice per diet and age, measured longitudinally on the same day each week. WebNov 13, 2024 · HFD-induced cognitive deficits may be associated with oxidative stress in the brain. Total levels of reactive oxygen species, superoxide, and peroxynitrite were significantly increased in mice fed HFDs (45% kcals from fat) compared to mice fed a control diet (10% kcals from fat) ( 92 ). WebJan 6, 2024 · When initiating the placement of mice on a high-fat diet at our facility, we usually include 15% more mice than absolutely needed for our study groups because some mice simply do not respond to the diet and need to be excluded from the experiment. The folic acid contents in the diets are shown in Table 1. immunoadsorption columns market