WebThe matrix metalloproteinases (MMPs) are a family of at least fifteen secreted and membrane-bound zinc-endopeptidases. Collectively, these enzymes can degrade all of the components of the extracellular matrix, including fibrallar and non-fibrallar collagens, fibronectin, laminin and basement membran … Web[1] List of COMT inhibitors [ edit] entacapone (Comtan, Comtess, Stalevo) nebicapone nitecapone opicapone (Ongentys) tolcapone (Tasmar) Entacapone and opicapone are peripheral inhibitors, unable to cross the blood-brain barrier. Tolcapone is able to cross the blood-brain barrier. [2]
Janus kinase inhibitor - Wikipedia
WebArachidonate 5-lipoxygenase inhibitor. Arachidonate 5-lipoxygenase inhibitors are compounds that slow or stop the action of the arachidonate 5-lipoxygenase (5-lipoxygenase or 5-LOX) enzyme, which is responsible for the production of inflammatory leukotrienes. The overproduction of leukotrienes is a major cause of inflammation in asthma ... WebSelective serotonin reuptake inhibitors (SSRI): sertraline, citalopram, fluoxetine; Amitriptyline; Codeine; Caffeine; Inducers. Inducers increase the expression level of … cigna healthcare today
Enzyme Inducer - an overview ScienceDirect Topics
WebAngiotensin-converting enzyme inhibitor (ACE inhibitors) drugs include Benazepril (Lotensin), Captopril (Capoten), Enalapril/Enalaprilat (Vasotec oral and injectable), … WebEnzyme inhibitors can be used as labels in much the same manner as coenzymes (see Fig. 13 ). S -substituted ethoxymethylphosphonothioates are irreversible inhibitors of acetylcholinesterase. Conjugation of haptens such as thyroxine and theophylline to the sulfur does not affect the inhibition. WebAmitriptyline, clozapine, desipramine, flecainide, haloperidol, nortriptyline, risperidone, and valbenazine are examples of drugs that are eliminated by CYP2D6 metabolism. The presence of CYP2D6 inhibitors can increase levels of these drugs. cilliers rademeyer